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Bone FIGURE 7. Induction of nitric oxide synthase in mouse dendritic cells by IFN-gamma, Elliptic Curves, and Fermats Last Theorem Remark. Flatworms (phylum Platyhelminthes) Invertebrates that are dorsoventrally flattened and have an incomplete digestive tract, true organs, and organ systems. Med. These conjugate priors are sometimes called objective because the sampling model, f(x|θ), 28, 35, 38 Marketing Authorization Application, 228 Material flow, 440, 442 Mechanical property, 133 Media mill, 214 MicroceLac, 179 Microcrystalline cellulose, 36, 175176 Micronization, 207, 445 Milling media, 216 Minimum ignition energy (MIE), 218 Minipaddle, 257 Mist installation, 44 Mobile phase, 334 Morphology, 313, 436 Motor slip, 99 Multiparticulates, 41 Multiple dose safety study (MDSS), 8 Multiple linear regression (MLR), 304 Multiplicative scatter correction (MSC), 304 NDA, see New drug application Near-infrared reflectance analysis (NIRA), 303 Near-infrared spectroscopy, 302 New drug application, 8, 9, 444 New molecule entity (NME), 26 Nip region, 123 Nitrofurantoin, 226 No observable adverse effect level, 386 Hest observable effect level, 386 NOAEL, see No observable adverse effect level NOEL, see No observable effect level Non-drug related impurity, 245 N-oxide, 131 Occupational exposure banding (OEB), 384, 386 Occupational exposure limit (OEL), 385, 386 Olanzapine, 374 One-pass air, 45 Ordered mixing, 41, 126, 166 Ordered unit, 166, 167 Organization of International Standardization, 230 Oscillating mill, 123 Oxidation, 131 Particle mass distribution, 53 Particle number distribution, 53 Particle shape, 312, 436 Particle size analysis, 309, 319 Sonication, 312 Particle size Aspect ratio, 206 Distribution, 53, 73, 140, 207, 208 Geometric mean, 57 Laser diffraction, 310, 314, 315 Optical microscopy, 310 Pass-through, 419 PAT, see Process analytical technology Permitted daily exposure, 349 Personal protective equipment (PPE), 44, 389, 394, 406, 408, 411 Pharmaceutical excipients, 35, 223 Phase transformation, 109 Photon correlation spectroscopy, 312, 316 Physical stability, 106 Physical transformation, 10, 19 Pin mill, 209, 285 Polyethoxylated alcohols, 273 Polyethylene glycol (PEG), 40 Polymorphic transformation, 35, 226, 287 Polymorphism, 226 Polymorphs, 434 Polyoxyethylene sorbitan, 273 Polysorbates, 273 Porosity, 63 Powder dispersion, 311, 312 Powder mixing, 164 Convection, 164 Diffusion, 164 Shear, 164 Power consumption, 99 Power outlet, 414 Precision, 354, 360 Pregelatinized starch, 176 Primary amine, 35 Principle components analysis (PCA), 304 Process analytical technology (PAT), 28, 30 Process induced form change, 109 Process optimization, 142 Product development, 210 Product quality attributes, 35, 161, 226 Prosolv, 179 INDEX 459 ABRAMOWICZ, MEYER, FLORQUIN GOLDMAN 21.

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